Wilms tumor is a type of kidney cancer that mostly affects children between the ages of 3 and 4.
Wilms tumor, also known as nephroblastoma It is a type of kidney cancer that usually affects children between the ages of 3 and 4.. Usually occurs in only one kidney. Although there is a risk of both kidneys being affected. Although it is a rare type of cancer, at age 5 it is very unusual for it to occur. This means that the child is out of danger.
However, because it is a tumor Therefore it is not very dangerous. Due to technological progress This makes it very easy to diagnose and treat. What causes children to suffer from this disease?If detected early and received appropriate treatment There is a high possibility of defeating it.
Symptoms of Wilms tumor
Although this tumor has different symptoms in each patient, and sometimes may not show symptoms But the most common symptoms are: Lumps in the abdomen, bloating, and abdominal pain.
However, these are not the only symptoms that children affected by Wilms’ tumor may have. Other symptoms include fever, blood in the urine, constipation, weight loss, dizziness and vomiting. and even difficulty breathing. As always, see a doctor if you notice that your child may have these symptoms. Because it is a rare tumor Therefore, it is likely that you do not have this disease. But it’s important to check if you have any doubts..
The cause is still unknown.
At this time it is not clear what causes the development of Wilms tumor, but it is believed that genetic makeup may play a role because tumors develop when there are abnormalities in the DNA. Cells grow and divide quickly. This accumulation of cancer cells forms a tumor. The reason it is believed to be hereditary is because in some cases abnormalities in this DNA can be passed from parent to child. However, this is all speculation as Wilms’ tumor is unfortunately a rare disease. Haven’t received enough educationAnd I don’t know if this might be some kind of connection or not.
There are several risk factors that can lead to the appearance of this tumor. But these are the most common:
- Background: African American children are at greater risk of Wilms’ tumor than Caucasian children. while Asian children were the least likely to present..
- Family history: As we have said, It is also a risk factor. This is because if any of your family members have this tumor. Your child will have a higher chance of developing this disease.
In the same way This tumor usually occurs in children who are born with a rare abnormality, such as an abnormality in the body or eyes. or various types of intellectual disabilities The most frequent are:
- WAGR syndrome: It is a rare genetic disorder that predisposes to Wilms tumor.. The main characteristic of children with this disease is the absence of pupils. Similarly, there may also be abnormalities in the genitals.
- Denys-Drash syndrome: This syndrome is also associated with Wilms tumor and is characterized by the development of disseminated mesangial sclerosis, pseudohermaphroditism, and nephrobastoma.
- Beckwith-Wiedemann syndrome: This is a genetic disorder related to Wilms’ tumor and is unique because people with the disease have internal organs. Outside the abdominal area, the tongue is large and overweight.It is caused by multiple mutations in the growth-controlling genes on chromosome 11 or by errors in genome typing.
to diagnose and treat this rare disease A complete medical history and thorough physical examination are required. The most frequently performed tests include the following:
- Physical exam: Here, the doctor will look for possible signs of a tumor, such as a lump in the kidney area or Some types of swollen stomach.
- Blood and urine tests: Although these tests cannot detect tumors, But they can give you some clues as to whether your kidneys are working properly or if you have kidney problems or low blood counts.
- Abdominal ultrasound: To check for foreign masses in the kidneys.
- Abdominal CT: If a foreign mass is detected on ultrasound. It is likely that CT will be done later. To know the size of the tumor or whether it has spread or not..
- Magnetic resonance: With this test You will find that the tumor has spread to other parts. of the body or not.
Set the scene
When it was proved that the child had Wilms tumor We will try to determine the extension or stage of the cancer:
- Stage 1: At this stage, the tumor is only found in one kidney. and can be surgically removed completely
- Stage 2: In this stage, the tumor has spread outside the kidney. Affecting other parts of the body near the kidneys, such as blood vessels At this point, it can still be removed surgically.
- Stage 3: In addition to spreading to nearby kidneys, It also affects distant areas such as lymph nodes. or other structures in the vicinity of the abdomen (In some cases, it may extend throughout the entire abdomen.) Although it can be operated on But there is a risk that if removed The tumor has spread throughout the body.Therefore, one must look for alternatives if the risk is very high.
- Stage 4: Here, the tumor has spread outside the kidney. and from the abdominal region to the lungs, liver, bones, or brain.
- Stage 5: Cancer cells are found in both kidneys. What is called bilateral participation?.
In most cases, this disease can be cured. With a survival rate of more than 90%.. However, it depends on the stage of the cancer. Tumor size and tumor characteristics and the child’s age This is because in teenagers and adults the survival prognosis is slightly lower.