This medicine, which is part of a group called Synthetic catecholamines are prescribed for cases of heart disease. and is administered by injection into a vein.
Dobutamine is a type of medicine that is sold in ampoules to be injected directly into the patient’s body. This medicine contains a sympathomimetic amine. specified in People with heart conditions or cardiac shockThe latter refers to the heart’s inability to send blood to other organs. of the body adequately This usually happens after being affected after a myocardial infarction. Dobumin stimulates beta-1 adrenergic receptors, a type of protein that affects smooth muscle and cardiovascular muscle, among others. It also belongs to a class of drugs known as adrenergic receptors. Synthetic catecholamines, which include dipexamine or isoproterenol, vasopressor drugs, or positive inotropes.
Health professionals usually prescribe this medicine to patients with the following conditions:
- cardiac compensation Caused by organic heart disease or after surgery, which requires short-term treatment.
- heart failure In the event of an impending heart transplant
- In the case where Shock from wastewater treatment Occurs in people who are old.
- Treatment Acute low heart function.
- Pharmacological stress test substances to try to identify coronary artery disease
- when it exists First level AV blockThis indicates a delay in electrical conduction from the atria to the ventricles.
- when it exists Second level AV block Mobitz type I (also known as Wenckebach phenomenon). In these, periodic failures of the conduction of electrical impulses are observed.
- In the case where The left ventricle of the heart is severely affected. After myocardial infarction and when damage to the heart fails with poor performance.
- in newborn patients Dobutamine can be prescribed in cases of: Low blood flow in the system During the first 24 hours of life
Contraindications and precautions
When starting treatment with dobutamine as directed by your doctor A number of conditions must be taken into account that may make drug administration ineffective. If you experience any of the following problems: The health professional must be informed..
- History of hypersensitivity to dobutamine.
- Predisposition to suffer from atrial fibrillation or persistent ventricular tachycardia.
- In the case of an aneurysm or aneurysm
- In the case of low volume
- Obstruction of left ventricular outflow tract.
- Stenosis of the left coronary artery
- If you have suffered a myocardial infarction in the past month.
- If the ultrasound images produced by the medical test are of poor quality
- Major heart valve defects
- unstable angina
- severe heart failure
- In cases of pericarditis, myocarditis or acute endocarditis.
- Obstruction of ventricular filling, such as constrictive pericarditis or tamponade.
- High blood pressure that is not properly controlled or treated.
Like other medicines Dobutamine can cause symptoms such as:
- Reaction at the injection site such as yellow fever – due to inflammation of the veins where the medicine was applied – or, to a lesser extent, skin necrosis – destruction of skin tissue.
- Heart rate increases and blood pressure
- Development of ventricular tachycardia after drug administration.
- Nausea and vomiting
- Chest pain
- Hypotension: A reduction in blood pressure, which usually resolves with a reduction in the administered dose or with complete withdrawal of the drug.
- Heart palpitations
- Difficulty breathing due to feeling of lack of air.
- Paresthesia or cramping in the legs
How to store dobutamine
drug Should be stored in the refrigerator. Protect from direct light. and if diluted for injection Under no circumstances should it be stored at room temperature for a maximum of 24 hours. The expiration date of the medicine is indicated on the package and it is strongly recommended to discard the medicine in time.
Interactions with other medications
In cases where the patient has already been treated with other medicines and the doctor does not know It is important to be informed to avoid possible interactions between the two drugs. Although there is no evidence that this situation will occur. Previous studies indicate that dobutamine may have no effect. If the person has previously taken α2 blocking drugs and has increased peripheral vascular resistance. For its part, concomitant consumption of dobutamine and sodium nitroprusside may promote the development of increased cardiac arrhythmias. The same is true for low pulmonary pressure.
The possibility of getting poisoned while taking dobutamine is highly unlikely. In any case If the patient has any of the following symptoms: It is important to contact your doctor quickly. : :
- loss of appetite nausea and vomiting
- high blood pressure
In the event of an overdose, the first measures to be taken are: Stop treatment immediately. with medication. Additionally, lines will be lined up for affected individuals and proper ventilation will be checked. In severe cases Certain medications may be needed to correct possible cardiac conditions.
Other situations to consider
- Drug administration in pregnant women: The adverse effects of dobutamine administration on the fetus are currently unknown. That is, it will cause category B risk in pregnancy. In any case, the doctor himself must assess the situation and determine whether the use of the drug will pose a risk to both the mother and the child.
- Dobutamine consumption in lactating women : There is an incompatibility that results in the need to suspend breastfeeding during the time of maternal exposure.
- Driving Compatibility : There are no potential negative effects of drug consumption on driving ability. Of course, extreme caution is recommended because of unpredictable consequences.
- As happens with the initiation of any drug treatment. Its consumption must be determined by a health professional. After he has personally assessed the patient’s situation and condition, Dobutamine should not be taken by prescription. Always follow the doctor’s advice. and never voluntarily stopped treatment.